Beamer, Lesa J.: search on Z-Library

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1

A missense variant remote from the active site impairs stability of human phosphoglucomutase 1

Stiers, Kyle M., Hansen, Reed P., Daghlas, Bana A., Mason, Kelly N., Zhu, JianâShe, Jakeman, David L., Beamer, Lesa J.

Journal:

Journal of Inherited Metabolic Disease

Year:

2020

File:

PDF, 2.85 MB

2020

2

Quaternary structure, conformational variability and global motions of phosphoglucosamine mutase

Ritcha Mehra-Chaudhary, Jacob Mick, John J. Tanner, Lesa J. Beamer

Journal:

Year:

2011

Language:

english

File:

PDF, 526 KB

english, 2011

3

The BPI/LBP family of proteins: A structural analysis of conserved regions

Lesa J. Beamer, Stephen F. Carroll, David Eisenberg

Journal:

Protein Science

Year:

1998

Language:

english

File:

PDF, 3.68 MB

english, 1998

4

A Coevolutionary Residue Network at the Site of a Functionally Important Conformational Change in a Phosphohexomutase Enzyme Family

Lee, Yingying, Mick, Jacob, Furdui, Cristina, Beamer, Lesa J., Buckle, Ashley M.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.74 MB

english, 2012

5

A Hotspot for Disease-Associated Variants of Human PGM1 Is Associated with Impaired Ligand Binding and Loop Dynamics

Stiers, Kyle M., Beamer, Lesa J.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.56 MB

english, 2018

6

Kinetic Analyses of Keap1–Nrf2 Interaction and Determination of the Minimal Nrf2 Peptide Sequence Required for Keap1 Binding Using Surface Plasmon Resonance

Yu Chen, Daigo Inoyama, Ah-Ng Tony Kong, Lesa J. Beamer, Longqin Hu

Journal:

Chemical Biology & Drug Design

Year:

2011

Language:

english

File:

PDF, 508 KB

english, 2011

7

Mutations in hereditary phosphoglucomutase 1 deficiency map to key regions of enzyme structure and function

Beamer, Lesa J.

Journal:

Journal of Inherited Metabolic Disease

Year:

2015

Language:

english

File:

PDF, 3.13 MB

english, 2015

8

Phosphorylation-Dependent Effects on the Structural Flexibility of Phosphoglucosamine Mutase from Bacillus anthracis

Stiers, Kyle M., Xu, Jia, Lee, Yingying, Addison, Zachary R., Van Doren, Steven R., Beamer, Lesa J.

Journal:

Year:

2017

Language:

english

File:

PDF, 7.38 MB

english, 2017

9

Phosphorylation in the Catalytic Cleft Stabilizes and Attracts Domains of a Phosphohexomutase

Xu, Jia, Lee, Yingying, Beamer, Lesa J., Van Doren, Steven R.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 3.42 MB

english, 2015

10

Multiple Ligand-Bound States of a Phosphohexomutase Revealed by Principal Component Analysis of NMR Peak Shifts

Xu, Jia, Sarma, Akella V. S., Wei, Yirui, Beamer, Lesa J., Van Doren, Steven R.

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 6.33 MB

english, 2017

11

Backbone Flexibility, Conformational Change, and Catalysis in a Phosphohexomutase from Pseudomonas aeruginosa †‡

Schramm, Andrew M., Mehra-Chaudhary, Ritcha, Furdui, Cristina M., Beamer, Lesa J.

Journal:

Year:

2008

Language:

english

File:

PDF, 4.16 MB

english, 2008

12

Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction

Hu, Longqin, Magesh, Sadagopan, Chen, Lin, Wang, Lili, Lewis, Timothy A., Chen, Yu, Khodier, Carol, Inoyama, Daigo, Beamer, Lesa J., Emge, Thomas J., Shen, Jian, Kerrigan, John E., Kong, Ah-Ng Tony, D

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.34 MB

english, 2013

13

Structure and characterization of a class 3B proline utilization A: ligand-induced dimerization and importance of the C-terminal domain for catalysis

Korasick, David, Gamage, Thameesha T, Christgen, Shelbi, Stiers, Kyle M, Beamer, Lesa J., Henzl, Michael T, Becker, Donald F, Tanner, John J.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 6.68 MB

english, 2017

14

The implications of the structure of the bactericidal/permeability-increasing protein on the lipid-transfer function of the cholesteryl ester transfer protein

Can Bruce, Lesa J Beamer, Alan R Tall

Journal:

Current Opinion in Structural Biology

Year:

1998

File:

PDF, 882 KB

1998

15

Focus Issue: Stress under the Sun: Spotlight on Ultraviolet-B Responses || Interallelic Complementation at the Ubiquitous Urease Coding Locus of Soybean

Ariel Goldraij, Lesa J. Beamer and Joe C. Polacco

Journal:

PLANT PHYSIOLOGY

Year:

2003

File:

PDF, 2.18 MB

2003

16

Defining the Phenotype and Assessing Severity in Phosphoglucomutase-1 Deficiency

Wong, Sunnie Yan-Wai, Beamer, Lesa J., Gadomski, Therese, Honzik, Tomas, Mohamed, Miski, Wortmann, Saskia B., Brocke Holmefjord, Katja S., Mork, Marit, Bowling, Francis, Sykut-Cegielska, Jolanta, Koch

Journal:

The Journal of Pediatrics

Year:

2016

Language:

english

File:

PDF, 1.16 MB

english, 2016

17

Evolutionary trace analysis of the α-D-phosphohexomutase superfamily

Grant S. Shackelford, Catherine A. Regni, Lesa J. Beamer

Journal:

Protein Science

Year:

2004

Language:

english

File:

PDF, 401 KB

english, 2004

18

Crystal Structure of PMM/PGM: An Enzyme in the Biosynthetic Pathway of P. aeruginosa Virulence Factors

Catherine Regni, Peter A Tipton, Lesa J Beamer

Journal:

Year:

2002

Language:

english

File:

PDF, 484 KB

english, 2002

19

Structural and dynamical description of the enzymatic reaction of a phosphohexomutase

Stiers, Kyle M., Graham, Abigail C., Zhu, Jian-She, Jakeman, David L., Nix, Jay C., Beamer, Lesa J.

Journal:

Structural Dynamics

Year:

2019

Language:

english

File:

PDF, 2.29 MB

english, 2019

20

The three-dimensional structure of human bactericidal/permeability-increasing protein: Implications for understanding protein–lipopolysaccharide interactions

Lesa J. Beamer, Stephen F. Carroll, David Eisenberg

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 473 KB

english, 1999

21

Synchrotron-based macromolecular crystallography module for an undergraduate biochemistry laboratory course

Stiers, Kyle M., Lee, Christopher B., Nix, Jay C., Tanner, John J., Beamer, Lesa J.

Journal:

Journal of Applied Crystallography

Year:

2016

Language:

english

File:

PDF, 747 KB

english, 2016

22

Sequence-structure relationships, expression profiles, and disease-associated mutations in the paralogs of phosphoglucomutase 1

Muenks, Andrew G., Stiers, Kyle M., Beamer, Lesa J., Zhang, Yang

Journal:

Year:

2017

Language:

english

File:

PDF, 10.00 MB

english, 2017

23

Synthesis, Derivatization, and Structural Analysis of Phosphorylated Mono-, Di-, and Trifluorinated d -Gluco-heptuloses by Glucokinase: Tunable Phosphoglucomutase Inhibition

Zhu, Jian-She, Stiers, Kyle M., Winter, Sherany M., Garcia, Anthony D., Versini, Antoine F., Beamer, Lesa J., Jakeman, David L.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.69 MB

english, 2019

24

The 1.7 Å crystal structure of BPI: a study of how two dissimilar amino acid sequences can adopt the same fold

Gary Kleiger, Lesa J. Beamer, Robert Grothe, Parag Mallick, David Eisenberg

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 709 KB

english, 2000

25

Focus Issue: Stress under the Sun: Spotlight on Ultraviolet-B Responses || Interallelic Complementation at the Ubiquitous Urease Coding Locus of Soybean

Ariel Goldraij, Lesa J. Beamer and Joe C. Polacco

Journal:

PLANT PHYSIOLOGY

Year:

2003

Language:

english

File:

PDF, 2.18 MB

english, 2003

26

Crystal structure of a bacterial phosphoglucomutase, an enzyme involved in the virulence of multiple human pathogens

Ritcha Mehra-Chaudhary, Jacob Mick, John J. Tanner, Michael T. Henzl, Lesa J. Beamer

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2011

Language:

english

File:

PDF, 2.26 MB

english, 2011

27

Identification of an essential active-site residue in the α- d -phosphohexomutase enzyme superfamily

Lee, Yingying, Mehra-Chaudhary, Ritcha, Furdui, Cristina, Beamer, Lesa J.

Journal:

Year:

2013

Language:

english

File:

PDF, 704 KB

english, 2013

28

Solution NMR of a 463-Residue Phosphohexomutase: Domain 4 Mobility, Substates, and Phosphoryl Transfer Defect

Sarma, Akella V. S., Anbanandam, Asokan, Kelm, Allek, Mehra-Chaudhary, Ritcha, Wei, Yirui, Qin, Peiwu, Lee, Yingying, Berjanskii, Mark V., Mick, Jacob A., Beamer, Lesa J., Van Doren, Steven R.

Journal:

Year:

2012

Language:

english

File:

PDF, 8.57 MB

english, 2012

29

Crystal Structure of GDP-Mannose Dehydrogenase: A Key Enzyme of Alginate Biosynthesis in P. aeruginosa †,‡

Snook, Christopher F., Tipton, Peter A., Beamer, Lesa J.

Journal:

Year:

2003

Language:

english

File:

PDF, 839 KB

english, 2003

30

Development of a Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay for the Inhibition of Keap1âNrf2 ProteinâProtein Interaction

Lee, Sumi, Abed, Dhulfiqar Ali, Beamer, Lesa J., Hu, Longqin

Journal:

Year:

2020

File:

PDF, 1.06 MB

2020

31

Detecting distant relatives of mammalian LPS-binding and lipid transport proteins

Lesa J. Beamer, Daniel Fischer, David Eisenberg

Journal:

Protein Science

Year:

1998

Language:

english

File:

PDF, 2.04 MB

english, 1998

32

Enzyme dysfunction at atomic resolution: Disease-associated variants of human phosphoglucomutase-1

Beamer, Lesa J.

Journal:

Year:

2020

File:

PDF, 1.01 MB

2020

33

Domain motion and interdomain hot spots in a multidomain enzyme

Gwo-Yu Chuang, Ritcha Mehra-Chaudhary, Chi-Ho Ngan, Brandon S. Zerbe, Dima Kozakov, Sandor Vajda, Lesa J. Beamer

Journal:

Protein Science

Year:

2010

Language:

english

File:

PDF, 404 KB

english, 2010

34

Structural Basis of Diverse Substrate Recognition by the Enzyme PMM/PGM from P. aeruginosa

Catherine Regni, Laura Naught, Peter A Tipton, Lesa J Beamer

Journal:

Year:

2004

Language:

english

File:

PDF, 285 KB

english, 2004

35

Induced structural disorder as a molecular mechanism for enzyme dysfunction in phosphoglucomutase 1 deficiency

Stiers, Kyle M., Kain, Bailee N., Graham, Abigail C., Beamer, Lesa J.

Journal:

Journal of Molecular Biology

Year:

2016

Language:

english

File:

PDF, 592 KB

english, 2016

36

Structural and dynamical description of the enzymatic reaction of a phosphohexomutase

Stiers, Kyle M., Graham, Abigail C., Zhu, Jian-She, Jakeman, David L., Nix, Jay C., Beamer, Lesa J.

Journal:

Structural Dynamics

Year:

2019

File:

PDF, 2.29 MB

2019

37

Inhibitory evaluation of αPMM/PGM from Pseudomonas aeruginosa: chemical synthesis, enzyme kinetic and protein crystallographic study

Zhu, Jian-She, Stiers, Kyle M., Soleimani, Ebrahim, Groves, Brandon R, Beamer, Lesa Jean, Jakeman, David L.

Journal:

Journal of Organic Chemistry

Year:

2019

Language:

english

File:

PDF, 811 KB

english, 2019

38

Crystallization of the chaperone protein SecB

Alice Vrielink, Lesa Beamer, Thanh Le, David Eisenberg

Journal:

Protein Science

Year:

1995

Language:

english

File:

PDF, 1.20 MB

english, 1995

39

Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

Lo, Shih-Ching, Li, Xuchu, Henzl, Michael T, Beamer, Lesa J, Hannink, Mark

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 410 KB

english, 2006

40

A simple pressure cell and delivery system for the preparation of Xe derivatives for protein crystallography

Stowell, Michael H. B., Soltis, S. Michael, Kisker, Caroline, Peters, John W., Schindelin, Hermann, Rees, D. C., Cascio, Duilio, Beamer, Lesa, Hart, John, Whitby, Frank G.

Journal:

Review of Scientific Instruments

Year:

1996

Language:

english

File:

PDF, 972 KB

english, 1996

41

Conservation of Functionally Important Global Motions in an Enzyme Superfamily across Varying Quaternary Structures

Emily K. Luebbering, Jacob Mick, Ranjan K. Singh, John J. Tanner, Ritcha Mehra-Chaudhary, Lesa J. Beamer

Journal:

Journal of Molecular Biology

Year:

2012

Language:

english

File:

PDF, 1.26 MB

english, 2012

42

Data on the phosphorylation state of the catalytic serine of enzymes in the α-D-phosphohexomutase superfamily

Lee, Yingying, Furdui, Cristina, Beamer, Lesa J.

Journal:

Year:

2017

Language:

english

File:

PDF, 661 KB

english, 2017

43

Allosterism and Cooperativity in Pseudomonas aeruginosa GDP-Mannose Dehydrogenase †

Naught, Laura E., Gilbert, Sunny, Imhoff, Rebecca, Snook, Christopher, Beamer, Lesa, Tipton, Peter

Journal:

Year:

2002

Language:

english

File:

PDF, 101 KB

english, 2002

44

Breaking the covalent connection: Chain connectivity and the catalytic reaction of PMM/PGM

Andrew M. Schramm, Dale Karr, Ritcha Mehra-Chaudhary, Steven R. Van Doren, Cristina M. Furdui, Lesa J. Beamer

Journal:

Protein Science

Year:

2010

Language:

english

File:

PDF, 312 KB

english, 2010

45

Refined 1.8 Å crystal structure of the λ repressor-operator complex

Lesa J. Beamer, Carl O. Pabo

Journal:

Journal of Molecular Biology

Year:

1992

Language:

english

File:

PDF, 15.07 MB

english, 1992

46

Asp263 missense variants perturb the active site of human phosphoglucomutase 1

Stiers, Kyle M., Graham, Abigail C., Kain, Bailee N., Beamer, Lesa J.

Journal:

Year:

2017

Language:

english

File:

PDF, 430 KB

english, 2017

47

Roles of Active Site Residues in Pseudomonas aeruginosa Phosphomannomutase/Phosphoglucomutase †

Naught, Laura E., Regni, Catherine, Beamer, Lesa J., Tipton, Peter A.

Journal:

Year:

2003

Language:

english

File:

PDF, 222 KB

english, 2003

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